Comparative Study of Corticotrphin Vs Vigabatrin Therapy in Infantile Spasm
نویسنده
چکیده
Twenty six patients were diagnosed as infantile spasm, on the basis of fixed criteria and they were divided into symptomatic (17 patients) and cryptogenic (9 patients) groups according to history, presentation and investigations. Corticotrophin as Tetracosactrin was given to eleven patients and fifteen patients received Vigabatrim (VGB). The response to VGB was significant (73%) compared to steroids (63%), irrespective of the etiology, thus emphasizing that VGB could be considered as the first line therapy for infantile spasm.
منابع مشابه
Safety and Efficacy of Vigabatrin for the Treatment of Infantile Spasms
In 2009, vigabatrin became the first FDA approved medication for the treatment of infantile spasms in the United States. There are few well-designed prospective studies comparing the drug to placebo or other modalities used in the treatment of infantile spasms. The available data have demonstrated that vigabatrin is efficacious in the treatment of infantile spasms regardless of underlying etiol...
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